The SelectedIndexChanged event occurs when the user selects a new item in the drop-down list.
The SelectedIndexChanged event does not fire unless the AutoPostBack property is True.
The SelectedIndexChanged event handler receives two arguments:
- The RadComboBox that is loading items. This argument is of type object, but can be cast to the RadComboBox type.
- An EventArgs object. This object has the following properties for identifying what has changed:            - Text is the text of the item that was just selected.
- Value is the value of the item that was just selected.
- OldText is the text of the item that was previously selected
- OldValue is the value of the item that was previously selected
 
Use the SelectedIndexChanged event handler to respond in server-side code when the user changes the current selection:
ASPX code:
<telerik:radcombobox 
  id="RadComboBox1" 
    runat="server" 
    autopostback="True" 
    onselectedindexchanged="RadComboBox1_SelectedIndexChanged">
</telerik:radcombobox>C# code behind:
private void RadComboBox1_SelectedIndexChanged(object o, Telerik.Web.UI.RadComboBoxSelectedIndexChangedEventArgs e)
{
    Label1.Text = "You selected " + e.Text + " item";
}  
 
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